The Endress+Hauser Raman flow assembly is a specialized setup designed to integrate Raman spectroscopy into downstream bioprocessing applications. Here’s a breakdown of its key features:
- Efficient Downstream Analysis: Optimizes Raman analysis for low-turbidity, low-volume samples commonly encountered in downstream bioprocessing stages like chromatography and filtration.
- Flow Cell and Flow Bench: Comprises a flow cell for sample containment and a flow bench for housing the flow cell. The flow bench enables easy swapping of flow cells without interrupting the process or compromising sterility.
- Rxn-10 Probe Compatibility: Designed to work seamlessly with the Endress+Hauser Rxn-10 Raman probe, creating a complete Raman spectroscopy system for inline analysis within bioprocessing workflows.
- Enhanced Signal Collection: Optimizes the Raman signal collection process for these specific sample types, leading to improved data quality and sensitivity for accurate analysis.
- Real-Time Monitoring: Enables continuous, real-time monitoring of critical bioprocess parameters within the flow stream, providing valuable insights for process optimization and control.
Benefits:
- Faster Process Optimization: Provides real-time data for rapid process adjustments and optimization in downstream bioprocessing.
- Improved Product Quality: Enables closer monitoring of bioprocess parameters, potentially leading to improved product quality and consistency.
- Simplified Maintenance: The flow bench design allows for easy flow cell replacement, minimizing downtime and simplifying maintenance procedures while maintaining sterility.
- Scalability: Compatible with the Raman calibration and verification kit, ensuring data transferability when scaling up processes from development to production.
In essence, the Endress+Hauser Raman flow assembly bridges the gap between lab-based Raman analysis and real-world downstream bioprocessing. It offers real-time monitoring capabilities, optimized data collection, and streamlined maintenance procedures, making it a valuable tool for bioprocess engineers and researchers seeking to improve process control and product quality in downstream bioprocessing applications.
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